Lamp based detection of sars-cov-2 with low-cost off-the-shelf components

2020 
This paper reports the design, development, and testing of a novel, yet simple and low-cost portable device for rapid SARS-CoV-2 detection The device performs loop mediated isothermal amplification (LAMP) and provides visually distinguishable images of the fluorescence emitted from the samples The device utilises an aluminium block embedded with a cartridge heater for isothermal heating of the sample and a single-board computer and camera for fluorescence detection The device demonstrates promising results within 20 minutes using clinically relevant starting concentrations of the synthetic template © 2020 CBMS-0001
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