Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups

Charles David Jones,Mark Alan Winter,Kenneth Steven Hirsch,Nancy B. Stamm,Harold Mellon Taylor,Howard E. Holden,James D. Davenport,Eriks V. Krumkalns,Robert George Suhr

Estrogen synthetase inhibitors. 2. Comparison of the in vitro aromatase inhibitory activity for a variety of nitrogen heterocycles substituted with diarylmethane or diarylmethanol groups

1990

Charles David Jones
Mark Alan Winter
Kenneth Steven Hirsch
Nancy B. Stamm
Harold Mellon Taylor
Howard E. Holden
James D. Davenport
Eriks V. Krumkalns
Robert George Suhr

The preparation and in vitro aromatase inhibitory activity of a wide variety of heterocyclic (4,4'-dichlorodiphenyl) methanes and -methanols are described

Keywords:

Aromatase
Nitrogen
Biochemistry
Estrogen
Biological activity
Inhibitory postsynaptic potential
Organic chemistry
Enzyme inhibitor
Chemistry
In vitro
Imidazole
Stereochemistry
Pyrazole
Thiazole
Triazole
Pyrimidine
Isothiazole

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