Inactivation of complement by recombinant human C3 derivatives.
2006
In summary, the design of recombinant C3 molecules with tailor-made anti-complementary properties represents a novel approach for depletion or modulation of complement, the mechanism of which is based on the well-established anti-complementary reagent CVF. Moreover, the characteristics of the derivatives can enable further molecular analyses and insights into the mechanisms of convertase formation.
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