Risk factors leading to bile leakage after hepatectomy for hepatic alveolar echinococcosis

Objective To analyze the risk factors of bile leakage after operation of hepatic alveolar echinococcosis. Methods The clinical manifestations, laboratory examination, imaging features and operative data of 137 patients with hepatic alveolar echinococcosis were retrospectively analyzed. The clinical characteristics of bile leakage group (n=22) and non-bile leakage group (n=115) were compared and analyzed, and the Logistic regression model was used to explore the related factors of bile leakage. Results Preoperative liver function (AST, ALP, LDH), blood loss, blood transfusion, hepatic hilum invasion, preoperative PTCD, and regular resection were significantly different between the two groups. Logistic regression analysis showed that regular hepatectomy was a protective factor to avoid bile leakage. Hepatic hilum invasion was a risk factor for bile leakage. Conclusion The invasion of the hepatic hilum is an important factor of postoperative bile leakage. Regular hepatectomy can reduce the incidence of postoperative bile leakage. Key words: Echinococcosis; Hepatectomy; Postoperative complications; Risk factors