15N isotopic analyses: a powerful tool to establish links between seized 3,4-methylenedioxymethamphetamine (MDMA) tablets

In this study the 15N/14N isotopic ratios of 43 samples of 3,4-methylenedioxymethamphetamine (MDMA) samples were measured using Gas Chromatography–Combustion–Isotope-Ratio Mass Spectrometry (GC–C–IRMS). The results show a large discrimination between samples with a range of δ15N values between −16 and +19‰. Comparison between δ15N values and other physical and chemical parameters shows a strong relationship between δ15N and brand logo or composition. Thus, it could be assumed that tablets from different seizures probably originated from the same clandestine manufacturing source. Hence, 15N isotopic parameters provide an important additional tool to establish common origins between seizures of clandestine synthetic drugs.