Emulgel: A novel drug delivery system

Topical therapies in cream, ointment, gel and lotion formulation, are an important component of dermatological therapeutic armamentarium. They are relatively free of serious side effects. Emulgel, mixture of emulsion and gel, is relatively a new and novel topical drug delivery system which has many advantages and potential uses in dermatology. An O/W or W/O emulsion from selected oils on the basis of solubility with suitable emulsifier and a gel formulation is prepared. Then emulsion is incorporated into gel base and an optimized formula of emulgel with different grades and different concentration of gelling agent by applying suitable statistical design is obtained. Excipients are selected on the basis of solubility. Oil portion leads to improvement in penetration. All selected excipients could be selected to assist pharmacological action of antimicrobial agent.