Non-Invasive Vs Invasive Procedures For Detection of H. Pylori Infection in Patients With Gastric Symptoms in Alkharj, Saudi Arabia

Objectives: H. pylori is detectable in nearly 100% of adult patients with duodenal ulcer and about 80% of patients with gastric ulcer. An association between H. pylori and gastric cancer is confirmed. In developing countries, where most children become infected by the age of 10, gastric cancer rates are very high. Diagnosis of Helicobacter pylori is achieved by invasive or non-invasive methods such as upper endoscopy, antral biopsies, H. pylori PCR of antral biopsies, H. pylori ELISA and H. pylori antigen detection in stool through ELISA technique. The aim of the current study is to compare the diagnostic performance of invasive and non- invasive diagnostic methods in the Kingdom of Saudi