Synthesis and Biological Evaluation of Some New2-propyl- 4(3H)-Quinazolinone Derivatives as Anti-bacteria

RESULT AND DISCUSSIONThe key starting material 2-propyl-4H- 3,1-ben-zoxazin-4-one (2) has been synthesized via theinteraction of butyroyl chloride with anthranilicacid in the presence of pyridine which yielded thecorresponding anthranil 1. Treatment of anthranil 1with acetic anhydride afforded the benzoxazinone2. The structure of anthranil 1 was proved from itsmicroanalytical data and its IR spectra (cm