A Novel Amperometric Sensor for Salicylic Acid Based on Molecularly Imprinted Polymer-Modified Electrodes

A novel electrochemical MIP-sensor for salicylic acid (SA) has been synthesized firstly by electropolymerizing o-phenylenediamine on glassy carbon electrode in presence of template molecule (salicylic acid). The response of the sensor to SA is investigated by square wave voltammetry (SWV). The linearity is obtained over a concentration range of 6 × 10−5 ∼ 1 × 10−4 mol/L (R2 = 0.9961). And the detection limit of SA is about 2 × 10−5 mol/L. The sensor exhibits good selectivity for salicylic acid by virtue of the interaction between molecularly imprinted binding sites and the template.