A Case of Zonal Syringocystadenoma Papilliferum of the Axilla Mimicking Verruca Vulgaris

Abstract: Syringocystadenoma papilliferum (SCAP) most frequently arises from an organoid nevus on the head and neck. Zonal or segmental lesions occurring in other locations are rare. Here, we report a case of a 39-year-old woman with an SCAP clinically mimicking verruca vulgaris in a zonal distribution on her right axilla after her birth. Histopathologic examination showed it to be a typical SCAP. Furthermore, the tumor had a warty surface, which histologically revealed some signs of viral infection. Although polymerase chain reactions for low- and high-risk human papilloma virus types were negative, the relationship of SCAP with viral infection needs further investigation.