Analgesic activity of hydroethanolic extract of Alternanthera sessilis in mice

The present study was conducted to evaluate the analgesic property of hydroethanolic extract of Alternanthera sessilis in mice. Hydroethanolic extract of Alternanthera sessilis was screened for its analgesic activity by using chemical method (Acetic acid induced writhing) for its peripheral antinociceptive activity and Eddy’s hot plate method for its central antinociceptive property at two dose levels (250 mg/kg body weight and 500 mg/kg body weight). The hydroethanolic extract of Alternanthera sessilis was found to have analgesic property with varying potencies in Chemical method and Hot plate method. The result was found to be significant in both the methods.