Properties and Analysis of Haloperidol and Its Dosage Forms
1961
Haloperidol (R 1625), a new synthetic organic compound belongs to a group of basic butyrophenones which constitute a distinct new class of neuroleptic substances. It occurs as a white, amorphous, or microcrystalline solid. It is only slightly soluble in water but can be dissolved in the presence of lactic or tartaric acid, giving stable solutions. Haloperidol may be formulated as multiple-dose solution for oral administration, as solution for injection, or tablets. It can be determined in its dosage forms by common analytical procedures. Haloperidol is stable in its formulations over long periods of time.
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