L-leucine increases translation of RPS14 and LARP1 in erythroblasts from del(5q) myelodysplastic syndrome patients

Deletion of the long arm of chromosome 5 [del(5q)] is the most common cytogenetic abnormality found in the myelodysplastic syndromes (MDS).[1][1] Patients with the 5q-syndrome have macrocytic anemia and the del(5q) as the sole karyotypic abnormality.[1][1] Haploinsufficiency of the ribosomal protein