Pyrazolopyrimidinone derivatives and their preparation and uses

The present invention, pyrazolopyrimidinone derivatives, provides a process for its preparation and application, its chemical structure is as follows, [Formula 1] Derivatives of the same kind, depending pharmacological tests, have potent PDE5 inhibitory activity, and, in some compounds is demonstrated to have a stronger PDE5 inhibitory activity than PDE6. The low toxicity of most compounds. Derivatives of the same kind are clinically, can be used to improve or treat symptoms or diseases including Kokorono vascular system, urinary system conditions or diseases, particularly erectile dysfunction.