A phase II trial of vandetanib (ZD6474) in children and adults with wild-type gastrointestinal stromal tumors.

John Glod,Fernanda I. Arnaldez,Lori Wiener,Melissa Amaya,Joanne Derdak,Ramaprasad Srinivasan,W. M. Linehan,Paul S. Meltzer,Markku Miettenen,Seth M. Steinberg,Brigitte C. Widemann

A phase II trial of vandetanib (ZD6474) in children and adults with wild-type gastrointestinal stromal tumors.

2016

John Glod
Fernanda I. Arnaldez
Lori Wiener
Melissa Amaya
Joanne Derdak
Ramaprasad Srinivasan
W. M. Linehan
Paul S. Meltzer
Markku Miettenen
Seth M. Steinberg
Brigitte C. Widemann

11009Background: Gastrointestinal stromal tumors (GIST) are resistant to cytotoxic chemotherapy and radiation therapy. The majority of GIST in pediatric patients are wild-type for KIT and PDGFRA (w...

Keywords:

Wild type
Cancer research
Stromal cell
Pathology
Vandetanib
Medicine
PDGFRA
Radiation therapy
cytotoxic chemotherapy
GiST

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