System for estimating and continuous exposure eyeccioncardiaca fraction and end-diastolic volume.

System for estimating a cardiac ejection fraction comprising: means (104) indicator injection for injecting an indicator at a position upstream of the heart according to a predetermined drive signal; a sensor (108) indicator concentration, which captures a concentration of local indicator in the blood at a downstream position and generating a signal indicator concentration, forming a channel for blood to the region from the upstream position including to the position downstream is inclusive; a monitor (116, 117) heart rate measuring a heart rate HR; means (112) processor to generate a channel model as preset function signal impeller and signal indicator concentration to continuously update the model to provide as output a parameter T decrease indicator a dilution curve patterned channel indicator, and for estimating the cardiac ejection fraction EF, characterized in that the EF is estimated as a predetermined function of the heart rate parameter T and heat decrease.