Incidence and outcomes of bepridil-induced interstitial pneumonia

Summary Background The incidence of bepridil-induced pulmonary toxicity, such as interstitial pneumonia, is still unknown. The aim of the present study was to evaluate the incidence of bepridil-induced pulmonary toxicity. Methods and results A total of 253 patients treated with bepridil between January 2009 and January 2011 were retrospectively evaluated. Eight out of the 222 evaluable patients (male/female: 5/3, age range: 64–97 years, average age: 80.5 years, median age: 81.0 years) showed bepridil-induced pulmonary toxicity. Conclusions The incidence of bepridil-induced pulmonary toxicity was 3.60% in our study population.