Candida albicans cell-type switching and functional plasticity in the mammalian host

In this Review, Noble and colleagues discuss the characteristics of the classic cell types of Candida albicans — yeast, hyphae, pseudohyphae and chlamydospores — as well as newly identified yeast-like morphotypes, including grey and gastrointestinally induced transition (GUT) cell types, and highlight emerging knowledge about their associations with different host niches and propensities towards virulence versus commensalism.