Abstract 11576: Factors Associated With Coronary Artery Disease Progression Assessed by Serial Coronary Computed Tomography Angiography

Introduction: Computed tomography coronary angiography (CCTA) allows for non-invasive coronary artery disease (CAD) phenotyping. Factors related to CAD progression are epidemiologically valuable. Objective: Identify factors associated with CAD progression in patients who underwent sequential CCTA testing. Methods: This is a retrospective study comprising a database of 5055 CCTA exams performed between May-2003 and Mar-2013 using 64 and 256-slice scanners, in which 382 individuals had sequential CCTA testing. Those with surgical revascularization or submitted to a percutaneous coronary intervention (PCI) between studies were excluded due to limitations in native vessel analysis and progression quantification, respectively. CAD progression was defined as any increase in the previously established segment stenosis score (calculated using the number of diseased segments and stenosis severity) in all coronary segments without stents (reestenosis was excluded from analysis). All studies were analyzed by a reade...