Multilineage differentiation potential of the cells derived from torn human rotator cuff

Issei Nagura, Takeshi Kokubu, Yutaka Mifune, Tomoyuki Muto, Hanako Nishimoto, Ryosuke Sakata, Masahiro Kurosaka Department of Orthopaedic Surgery, Kobe Rosai Hospital Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine Senior author: surf-trip@ams.odn.ne.jp Introduction Rotator cuff injuries are frequently encountered cause of pain and dysfunction in the shoulder. Clinical results of rotator cuff repair have been good. One of common complications is retear of the rotator cuff. Therefore, it is important of regeneration of the enthesis after the rotator cuff repair. While, we have already reported that chondrogenic differentiation potential of the cells derived from torn human rotator cuff [1]. Differentiation of the degenerated human rotator cuff has not been analyzed previously. In this study, we targeted the degenerated cells from the torn human rotator cuff and investigated whether the human rotator cuff derived cells have the capacity for multilineage differentiation in vitro.