식도암의 생존율에 영향을 미치는 인자

1993 
Esophageal carcinoma carries an extremely poor prognosis. Despite advances in medical technology, survival rates after diagnosis remain dismal. This report was attempted to analyse the survival rate and affecting factor in 76 cases of esophageal carcinoma patients. They received various modalities of treatment, and the median sruvival for each treatment group was 10.9 months in combined radiotherapy and chemotherapy (27 cases), 6 months in radiotherapy alone (10 cases), 13 months in combined therapy including surgery (20 cases), 4.5 months in chemotherapy alone (6 cases), and 5.7 months in conservative therapy (13 cases) (p< 0. 05, Peto-Wilcoxon method). The median survival by stage was 20. 7 months for stage I, 11. 2 rnonths for stage II, 6.9 months for stage III, and 5.7 months for stage lV (p<0.05, Peto-Wilcoxon method). Using survival as an outcome, a Cox-multivariate analysi was performed looking at age, location of lesion, length of lesion, TNM stage, type of treatment, hemoglobin level, albumin level, and weight loss. This analysis revealed significant predictors for increased survival, which were type of treatment and TNM stage (p<0.05). We concluded that the significant factors affecting the survival in esophageal carcinoma were treatment strategy an TNM stage.
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