The remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome

: RS3PE syndrome was diagnosed in a 83-year-old man with seronegative symmetrical polysynovitis with pitting oedema, which presented after a vehement acute beginning a remarkably favourable course. RS3PE syndrome, recently described, is characterized by a transient seronegative symmetrical synovitis with pitting oedema. The syndrome appears mainly in the aged. After a frequently acute crippling beginning, the prognosis is good. Plain and brief treatment will suffice.