Linkage and mutational analysis of the CDAN1 gene reveals genetic heterogeneity in congenital dyserythropoietic anemia type I

The congenital dyserythropoietic anemias (CDAs) are a heterogeneous group of genetic disorders of erythropoiesis characterized by anemia secondary to ineffective erythropoiesis and striking morphologic abnormalities of erythroblasts (reviewed in Wickramasinghe and Wood[1][1]). The autosomal