Correlación entre niveles séricos de PCR ultrasensible y factores de riesgo cardiovasculares en pacientes adultos con Diabetes Mellitus tipo 2, atendidos en el servicio de consulta externa de ndocrinología del Hospital General de las Fuerzas Armadas, ent

2019 
kground: The inflammatory process plays an important role in atherosclerotic cardiovascular disease, and considering in the pathogenesis of Type 2 Diabetes the insulin resistance state as pro-inflammatory, hs-CRP appears as one of the most studied markers to measure the inflammatory burn. The study`s objective is to assess the degree of correlation between the levels hs-CRP and cardiovascular risk factors in patients with diagnosis of Type 2 Diabetes. Type of study: observational, analytical, cross-sectional, correlation study to determine the degree of relationship between the variables. Place and subjects: patients between ages of 20 to 80 years, with diagnosis of Type 2 Diabetes, who came to Endocrinology consult of Military Hospital, period May and July of 2012. Main Outcome Measures: correlation- ship between serum levels of hs-CRP and cardiovascular risk factors. Results: We found a moderate significant positive correlation between hs-CRP with glycated hemoglobin (r. 0.55, p 0,01), a weak correlation with, body mass index (r. 0,27, p 0,05) and waist circumference in women (r. 0,37, p 0,01 ) and men (r. 0,25, p 0,05 )There was a very weak but significant positive correlation between hs-PCR with time of diagnosis, (r. 0.19, p 0,05), fibrinogen(r. 0.18, p 0,01)), levels of blood pressure (r. 0.17, p 0,05). A nonsignificant weak negative correlation with female gender (r. -0.153, p 0,057) and smoking (r. 0.11, p 0, 05) There was no correlation between hs-CRP with age, hypertension, lipid profile and Framingham score. Conclusions: We observed a statistically significant positive correlation between hs-CRP levels and glycated hemoglobin, Body Mass Index, waist circumference, fibrinogen levels, time of diagnosis and blood pressure.
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