Antimicrobial Cost Savings and Reduction in Clostridium Difficile Infection Rates Following Implementation of a Pediatric Antimicrobial Stewardship Program

antimicrobial stewardship program will lead to a reduction in antimicrobial usage and rates of CDI. • C. difficile infection (CDI) is a serious unintended consequence of antimicrobial use.1,2 • The incidence of CDI rises with cumulative antimicrobial exposure.3 • Incidence and mortality due to CDI in children have increased in the past decade.2,4-8 • Adult antimicrobial stewardship programs (ASPs) have been shown to reduce the rate of CDI.9--12