Catalytic Enantioselective Synthesis of a cis-β-Boronyl Cyclobutylcarboxyester Scaffold and Its Highly Diastereoselective Nickel/Photoredox Dual-Catalyzed Csp3–Csp2 Cross-Coupling to Access Elusive trans-β-Aryl/Heteroaryl Cyclobutylcarboxyesters

Kevin Nguyen,Helen A. Clement,Louise Bernier,Jotham Wadsworth Coe,William Farrell,Christopher John Helal,Matthew R. Reese,Neal W. Sach,Jack C. Lee,Dennis G. Hall

Catalytic Enantioselective Synthesis of a cis-β-Boronyl Cyclobutylcarboxyester Scaffold and Its Highly Diastereoselective Nickel/Photoredox Dual-Catalyzed Csp3–Csp2 Cross-Coupling to Access Elusive trans-β-Aryl/Heteroaryl Cyclobutylcarboxyesters

2021

Kevin Nguyen
Helen A. Clement
Louise Bernier
Jotham Wadsworth Coe
William Farrell
Christopher John Helal
Matthew R. Reese
Neal W. Sach
Jack C. Lee
Dennis G. Hall

Chiral cyclobutanes are components of numerous bioactive natural products, and consequently, they have also gained significant attention in medicinal chemistry. Optically enriched cyclobutylboronat...

Keywords:

Chirality (chemistry)
Combinatorial chemistry
Aryl
Catalysis
Nickel
Enantioselective synthesis
Chemistry
Cyclobutanes
Scaffold

Correction
Source
Cite
Save
Machine Reading By IdeaReader

References

Citations