EXOCRINE PANCREAS IN PARATHYROPRIVIC HYPOCALCEMIA : MORPHOFUNCTIONAL CHARACTERISTICS

Hypocalcemia caused by removal of the parathyroid glands results in abnormal secretory activity of pancreatic acinar cells, with secretion accumulating in these cells and interstitium. In addition, focal necrosis develops in the pancreas by day 30 after parathyroidectomy. These abnormalities are accompanied by a decrease in blood levels of pancreatic enzymes. Possible mechanisms of these changes are discussed.