Clozapine Treatment and Thrombocytopenia: a Case Report

Clozapine associated thrombocytopenia is a rare complication and there is limited published literature on this subject. The hematologic side effects of clozapine are usually associated with leukocytes and neutrophils, therefore its effects on thrombocytes might be ignored. Thrombocytopenia can cause mortality especially from bleeding when platelet count is below 10*109/L. We aimed to present a clozapine related trombocytopenia in a patient with schizophrenia who did not respond to any antipsychotics except clozapine and to review the literature on this subject.