One kind of Staphylococcus inhibitor

Effect of compounds of the present invention belongs to the field of biotechnology, relates to inhibitors of formula I to Staphylococcus; as a pharmaceutical compound and a method for preventing or treating bacterial infectious diseases. By biochemical and biological assay, the results showed the compound to the protein Staphylococcus epidermidis or Staphylococcus aureus invention aminoacyl -tRNA synthetases have a strong binding force, and can inhibit the synthetic activity of the enzyme, and activity on human tryptophyl -tRNA synthetases small; significantly inhibit the growth of Staphylococcus epidermidis and Staphylococcus aureus. At the minimum inhibitory concentration substantially non-toxic to mammalian cells. Inhibitors of the present invention, a pharmaceutical preventing or treating diseases caused by Staphylococcus can be prepared and formulated disinfectant.