Syntheses and odor properties of optically active dimethyl octenone and its analogs

Abstract The optically active isomers of dimethyl octenone, which is used in citrus accords, and its analogs, were synthesized from a common chiral intermediate prepared by the lipase-catalyzed desymmetrization of prochiral diol. The results of an olfactory evaluation of the prepared isomers are also reported.