Clinical Study of Extracorporeal Membrane Oxygenation in the Treatment of Acute Respiratory Distress Syndrome Secondary to Severe Acute Pancreatitis

Objective:To investigate the effect of extracorporeal membrane oxygenation in the treatment of acute respiratory distress syndrome secondary to severe acute pancreatitis (SAP).Methods:BM25 machine (Baxter, USA) and FDMO-08 hollow-fiber membrane oxygenator(Ningbo Yatai medical Instrument co. ltd) were used for the treatment of 10 patients with ARDS complicating SAP. Partial Pressure of Oxygen( PO_2) and carbondioxide( PaCO_2) were analyzed before and after treatment.Results:Clinical symptoms were singly improved in 6 out of 10 patient and 4 patients died. Hypoxemia was improved after treatment compared with that of before treatment (P0.05), but there was no significant difference in PaCO_2 (P0.05).Conclusion:Extracorporeal membrane oxygenation can effectively and rapidly increase the blood oxygen concentration of patients with severe ARDS complicating acute pancreatitis.