Preferential heterodimerization of a bispecific diabody based on a humanized anti-EGFR antibody 528

Ryutaro Asano1, Yukiko Sone1, Keiko Ikoma1, Hiroki Hayashi2, Takeshi Nakanishi1, Mitsuo Umetsu1, Yu Katayose2, Michiaki Unno2, Toshio Kudo3 and Izumi Kumagai1,4 Department of Biomolecular Engineering, Graduate School of Engineering, Tohoku University, Sendai 980-8579, Division of Gastroenterological Surgery, Department of Surgery, Graduate School of Medicine, Tohoku University, Sendai 980-8574 and Cell Resource Center for Biomedical Research, Institute of Development, Aging, and Cancer, Tohoku University, Sendai 980-8575, Japan