Pooled analysis of onapristone extended release (ONA ER) in metastatic cancer patients (pts): A review of liver safety.

Paul Cottu,Anuradha Jayaram,Antoine Italiano,Simon Pacey,Alexandra Leary,Robert Jones,Mario Campone,Anne Floquet,Dominique Berton-Rigaud,Catherine Lhomme,Marie Paule Sablin,Alice Susannah Bexon,Jacques Bonneterre,Gerhardt Attard,Paul B. Watkins

Pooled analysis of onapristone extended release (ONA ER) in metastatic cancer patients (pts): A review of liver safety.

2019

Paul Cottu
Anuradha Jayaram
Antoine Italiano
Simon Pacey
Alexandra Leary
Robert Jones
Mario Campone
Anne Floquet
Dominique Berton-Rigaud
Catherine Lhomme
Marie Paule Sablin
Alice Susannah Bexon
Jacques Bonneterre
Gerhardt Attard
Paul B. Watkins

e14647Background: ONA, a type I progesterone receptor (PR) antagonist, prevents PR activation by disrupting PR dimerization and DNA binding, and inhibits tumor progression. ONA (immediate release) ...

Keywords:

Oncology
Cancer
Pathology
Onapristone
Internal medicine
Medicine
pooled analysis
DNA
Tumor progression
extended release
Progesterone receptor
Cancer research
Antagonist

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