Antitumor effects of interferons

Numerous studies have been reported, examining the effects of Interferons (IFNs) on tumors of different type and histology in various animal systems. Both IFNs and IFN inducers have been used to study inhibitory effects on virus, chemical and radiation induced tumors as well as transplantable and spontaneous tumors. These have been reviewed extensively elsewhere (2, 33, 83)