Pathogenic distribution and antimicrobial resistance of Gram-negative bacillus causing pneumonia

OBJECTIVE To study the constituent ratio and drug resistance of gram-negative bacillus causing pneumonia so as to explore the scientific evidence of anti-infective treatment. METHODS A retrospective review was performed for 345 strains of gram negative bacillus from the sputum and lower respiratory tract secretion of patients with pneumonia.The bacterium spectrum and drug susceptibility testing results were statistically analyzed. RESULTS Among 387 isolates of gram-negative bacilli,the top five isolation rates were as the following: Pseudomonas aeruginosa(28.2%),Klebsiella pneunmoniae(19.9%),Acinetobacter baumannii,(14.5%),Escherichia coli(12.7%),Stenotrophomonas maltohpilia,(8.3%).The five important pathogens all showed serious drug resistance.The detection rates of pan-resistant PAE and ABA reached to 16.5% and 19.6%. CONCLUSION The clinicians in department of respiratory diseases should prescribe the antibiotics according to bacteriological testing and susceptibility testing results of patients with pneumonia.