Short and long term intraocular pressure changes after intravitreal injections of triamcinolone acetonide and bevacizumab in diabetic macular edema

Objective: To compare the short and long term intraocular pressure changes after intravitreal injections of triamcinolone acetonide and bevacizumab in diabetic macular edema cases presenting at Al-Shifa Trust Eye Hospital, Rawalpindi. Study Design: A hospital based randomized clinical trial. Subjects and Methods: The study was conducted from 01 Jan 2012 to 31st December 2012 on 60 patients with diabetic macular edema; 30 injected with intravitreal triamcinolone acetonide (IVTA) and 30 with intravitreal bevacizumab (IVB). IOP was recorded before injection, at 1week and 6 weeks after injections. All findings were recorded on proformas and results were analyzed using SPSS 13.0. Results: Difference in mean IOP of the two groups was not significant at base line (p=0.765) and 1 week (p=0.560). At 6 weeks, mean IOP in IVTA significantly raised from its base line mean IOP (paired sample t test, p