The Frank-Starling Mechanism Involves Deceleration of Cross-Bridge Kinetics and is Preserved in Failing Human Right Ventricular Myocardium
2015
Using a novel method that allows assessment of cross-bridge cycling at body temperature in intact muscles obtained from end-stage failing as well as nonfailing human hearts, we show cross-bridge cycling rate to be length dependent in the right ventricle but not to be altered by disease.
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