Intragenic DNA methylation prevents spurious transcription initiation

Francesco Neri,Stefania Rapelli,Anna Krepelova,Danny Incarnato,Caterina Parlato,Giulia Basile,Mara Maldotti,Francesca Anselmi,Salvatore Oliviero

Intragenic DNA methylation prevents spurious transcription initiation

2017

Francesco Neri
Stefania Rapelli
Anna Krepelova
Danny Incarnato
Caterina Parlato
Giulia Basile
Mara Maldotti
Francesca Anselmi
Salvatore Oliviero

Intragenic DNA methylation, dependent on Dnmt3b, protects the gene body from spurious entry of RNA Polymerase II and aberrant transcription initiation events.

Keywords:

Methylation
Cell biology
Gene
DNA
DNA methylation
Epigenetics
Transcription (biology)
RNA polymerase II
Genetics
DNMT3B
Biology
RNA polymerase
Gene expression
Promoter

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