Evaluation of the impact of computed high b-value diffusion-weighted imaging on prostate cancer detection.

Purpose The purpose of this study was to compare high b-value (b = 2000 s/mm2) acquired diffusion-weighted imaging (aDWI) with computed DWI (cDWI) obtained using four diffusion models—mono-exponential (ME), intra-voxel incoherent motion (IVIM), stretched exponential (SE), and diffusional kurtosis (DK)—with respect to lesion visibility, conspicuity, contrast, and ability to predict significant prostate cancer (PCa).