Increase in the hypothalamic tyrosine hydroxylase activity after lesion of the catecholaminergic neurons of the rat pontine tegmentum

: Hypothalamic tyrosine hydroxylase activity is increased 6 and 18 h after bilateral lesioning of the Locus Coerulues, in the Rat. An adrenocortical hypertrophy was observed previously, under the same experimental conditions. The neurochemical and neuroendocrinological implications of theses results are discussed.