4-YEAR-OLD NEURODEVELOPMENT AND EARLY LIFE DETERMINANTS ARE LONGITUDINALLY ASSOCIATED TO 11-YEAR-OLD ATTENTION FUNCTION

Background and Aims: Previous studies have found association between cognitive development at 4 years old and several early life determinants such as maternal social class, maternal smoking during pregnancy, being first born, breastfeeding, cord blood DDT levels, indoor levels of NO2, and atopy. This study aimed to assess the association between child neurodevelopment at age 4 and the development of attention function at 11 years. We also aimed to assess the early life determinants related to attention functioning at age 11. Methods: this study was based on a birth-cohort from Menorca, one of the Balearic Islands of the north-east coast of Spain. At 11 years old, 393 children were assessed with the Conners’ Continuous Performance Test – Second Edition (CPT-II). This is a 14-minute computerized measure of inhibitory control, sustained attention, vigilance, reaction time, and response variability. The three outcomes analyzed of CPT-II were Omissions, Comissions and Hit Reaction Time. At 4 years old were ass...