Epsilon amino caproic acid myopathy: additional features

Abstract In a patient with a proximal myopathy due to Epsilon Amino Caproic Acid (EACA) bedrest led to marked improvement even before withdrawal of the drug. A biopsy showed a selective necrosis of type I fibers. Plasma level of EACA was low and plasma level of lysine was normal. A 99m Technetium-MDP showed marked uptake in the affected muscles, whereas a 67 Gallium scan was negative.