Quinine-catalyzed enantioselective desymmetrization of meso-aziridines with benzenethiols
2008
Abstract Ring opening of meso -aziridines with benzenethiols utilizing quinine as an organocatalyst has been developed. The reaction proceeded smoothly in the presence of 10 mol % of quinine in CHCl 3 to afford β-amino sulfides in high yields and with moderate to good enantioselectivities.
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