Abstract 17076: Magnetocardiography-derived 3D Current Density Maps Show Increased Sensitivity and Localization of Ischemic Damage in High Risk Unstable Angina Patients

Background: Magnetocardiography (MCG) measures the magnetic field induced by the electrical current generated during the cardiac cycle. Since electric current is affected by ischemic damage, MCG can thereby be used to noninvasively detect and localize said damage due to acute coronary syndrome (ACS). Hypotheses: We hypothesize that a novel 3D current density mapping method for visualizing MCG is efficacious in detecting and localizing ischemic damage when compared to gold standard dismissal diagnosis as the primary measure. Methods: MCG-derived current density maps were created for a cohort of 28 prospectively enrolled high risk unstable angina (UA) patients diagnosed by ACC/AHA guidelines. The first 16 patients’ maps were used to calculate sensitivity and specificity in a single-blinded study. Unblinded normal (n = 11) and ischemic (n = 7) sub-cohorts were selected from the full cohort based on certain inclusion and exclusion criteria. The 17-segment AHA model was used to localize differences in electric...