Abstract 117: Transgelin: A New Gene Involved in LDL Endocytosis in Liver Cells Identified by a Whole-genome Crispr-cas9 Screen
2019
Familial hypercholesterolemia is caused by mutations in either LDL receptor (LDLR), ApoB-100, LDLRAP1, or PCSK9, but ~30% of patients lack these mutations, suggesting that unknown genes are also in...
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