Glucosephosphate dehydrogenase activity and reduced glutathione level in the erythrocytes of children with lymphoblastic leukemia

: The activity of glucose-6-phosphate dehydrogenase and the level of reduced glutathione were determined in the erythrocytes of children with acute lymphoblastic leukaemia treated by intensive combined chemotherapy (according to the authors from Memphis). The determinations were done before, during and after completion of treatment lasting about 3 years. A significant rise was observed in the activity of this enzyme and in the level of reduced glutathione in the groups of treated children and their fall to normal values after completion of treatment.