Epidermal Growth Factor Receptor (EGF-R) and HER-2/NEU p185 Protein Expression in Esophageal Cancer

Epidermal Growth Factor receptor (EGF-R) and p185 protein, encoded by oncogene neu, are structurally related proteins of the erb-B family involved in the growth control of several cancer types. Overexpression of both EGF-R and p185 seems to be related to malignant transformation in several cancer types [1].