Magnetic resonance assays of haloperidol in human serum albumin

Haloperidol is a commonly used neuroleptic drug associated with a range of side effects. The aim of the study was to determine in vitro interaction of haloperidol with human serum albumin (HSA) by 19F magnetic resonance spectroscopy (MRS) at 9.4 Tesla (T). The practical measurement based on fluorine resonance has been proposed to determine drug level in HSA at 37°C.