Diffuse Pulmonary Nodules with Bilateral Hilar Lymphadenopathy as a Clinical Presentation of Primary Amyloidosis with Pulmonary Involvement: A Case Report

Amyloidosis is a relatively rare disease in clinical practice. However, pulmonary involvement in patients with amyloidosis is common. We report a 46-year-old female who presented chronic cough with mild dyspnea on exertion for about 5 weeks. Chest radiography showed diffuse pulmonary nodules with bilateral hilar lymphadenopathy. Serum protein electrophoresis followed by immunofixation electrophoresis revealed a monoclonal band of IgG-λ specificity, and multifocal amyloid deposits were found in the lung biopsy via video-assisted thoracoscopic surgery. A diagnosis of primary amyloidosis with pulmonary involvement was confirmed.