Dna synthetic enzyme inhibitors

Disclosed are together find compounds having a DNA synthesis inhibiting activity, to provide new pharmaceutical compositions utilizing the compounds (DNA synthesis inhibitor, anticancer and anti-inflammatory agents). A general formula (1) or a compound represented by (2), or a pharmaceutically acceptable salt thereof, pharmaceutical compositions containing them as active ingredient (DNA synthesis inhibitor, anticancer, anti-inflammatory agents, and the like) on. (Wherein, R represents H or an alkyl group.) .BACKGROUND